Article

A dual function of TMEM70 in OXPHOS: assembly of complexes I and V

2019-07-10

Abstract excerpt

Protein complexes from the oxidative phosphorylation (OXPHOS) system are assembled with the help of proteins called assembly factors. We here delineate the function of the inner mitochondrial membrane protein TMEM70, in which mutations have been linked to OXPHOS deficiencies, using a combination of BioID, complexome profiling and coevolution analyses. TMEM70 interacts with complex I and V and for both complexes th...

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Literature Corpus work: 5edb8a1e-30bd-5e2f-9555-6e6186adf270
DOI: 10.1101/697185

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