Article

Statins do not reduce the parasite burden during experimental <i>Trypanosoma cruzi</i> infection

2025-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Cardiomyopathy is the most common pathology associated with Trypanosoma cruzi infection. Reports that statins have both cardioprotective and trypanocidal activity have generated interest in their potential as a therapeutic treatment. Using a highly-sensitive bioluminescent mouse model, we show that 5 days treatment with statins has no significant impact on parasite load. The free systemic conce...

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Literature Corpus work: e10a311a-54b3-5fdc-9bf0-6f26fdde9508
DOI: 10.1101/2025.01.30.635783

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