Article

Fat Tissue Regulates the Pathogenesis and Severity of Cardiomyopathy in Murine Chagas Disease

2020-11-26

Abstract excerpt

<h4>ABSTRACT</h4> Chronic Chagas cardiomyopathy (CCC) caused by a parasite Trypanosoma cruzi is a life-threatening disease in Latin America, for which there is no effective drug or vaccine. The pathogenesis of CCC is complex and multifactorial. Previously, we demonstrated T. cruzi infected mice lose a significant amount of fat tissue which correlates with progression of CCC. Based on this an investigation was u...

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Literature Corpus work: 08fa1561-7afb-5fd9-981d-5eb9372909d8
DOI: 10.1101/2020.11.25.397596

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