Article

Ontogenesis of the molecular response to sleep loss

2023-01-18

Abstract excerpt

Sleep deprivation (SD) results in profound cellular and molecular changes in the adult mammalian brain. Some of these changes may result in, or aggravate, brain disease. However, little is known about how SD impacts gene expression in developing animals. We examined the transcriptional response in the prefrontal cortex (PFC) to SD across postnatal development in male mice. We used RNA sequencing to identify functi...

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Literature Corpus work: e0fdbb40-9a51-5de0-be2e-6fc2bd7c9676
DOI: 10.1101/2023.01.16.524266

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