Article

A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating

2019-10-22

Abstract excerpt

<h4>ABSTRACT</h4> While the basic mechanisms of flavivirus entry and fusion are understood, little is known about the post-fusion events that precede RNA replication, such as nucleocapsid disassembly. We describe here a sensitive, conditionally replication-defective yellow fever virus (YFV) entry reporter, YFVΔSK/Nluc, to quantitively monitor the translation of incoming, virus particle-delivered genomes. We valid...

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Identifiers and source

Literature Corpus work: b5e9874c-6411-53fb-9717-6fd960385fd0
DOI: 10.1101/814764

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