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Article

Intricate relationships between naked viruses and extracellular vesicles in the crosstalk between pathogen and host

22 May 2018

Abstract excerpt

It is a long-standing paradigm in the field of virology that naked viruses cause lysis of infected cells to release progeny virus. However, recent data indicate that naked virus types of the Picornaviridae and Hepeviridae families can also leave cells via an alternative route involving enclosure in fully host-derived lipid bilayers. The resulting particles resemble extracellular vesicles (EV), which are 50 nm-1...

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PMID: 29789863
DOI: 10.1007/s00281-018-0678-9

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