Article

DeepCLIP: Predicting the effect of mutations on protein-RNA binding with Deep Learning

2019-09-05

Abstract excerpt

<h4>ABSTRACT</h4> Nucleotide variants can cause functional changes by altering protein-RNA binding in various ways that are not easy to predict. This can affect processes such as splicing, nuclear shuttling, and stability of the transcript. Therefore, correct modelling of protein-RNA binding is critical when predicting the effects of sequence variations. Many RNA-binding proteins recognize a diverse set of motifs...

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Literature Corpus work: e0c441b4-1278-5515-952d-ff800fedb7e4
DOI: 10.1101/757062

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