Article

A Signaling Network based Computational Model to Uncover Loop as the Novel Molecular Mechanisms for Medulloblastoma

2019-02-26

Abstract excerpt

Medulloblastoma (MB) is the most common malignant brain tumor in children. Despite aggressive therapy, about one-third of patients with MB still die, and survivors suffer severe long-term side effects due to the treatments. The poor post-treatment outcomes are tightly linked to unpredictable drug resistance. Therefore, before developing robust single drug or drug combination recommendation algorithms, uncovering t...

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Literature Corpus work: e0b5b53e-1e92-5fae-a8a0-a477b55cb926
DOI: 10.1101/561076

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