Article

Integrative Multi-Scale Network Simulation for Precision Drug Repurposing with PETS

2025-02-28

Abstract excerpt

Drug repurposing offers a promising strategy to accelerate therapeutic discovery for complex diseases; however, conventional approaches often overlook the multi-scale, dynamic nature of drug-induced perturbations. In this study, we introduce PETS (Predictive Evaluation of Therapeutic Simulations), an innovative in silico framework that synergistically integrates curated pathway models with multi-layer network prop...

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Identifiers and source

Literature Corpus work: 79627a9c-ccdf-55dd-b029-b135e450c590
DOI: 10.1101/2025.02.24.639994

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