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Article

Mass cytometry uncovers distinct blood myeloid phenotypes linked to clinical responses during gastric cancer chemoimmunotherapy.

Cancer immunology, immunotherapy : CII - 31 Mar 2026

Lim Sung Hee, An Minae, Heo You Jeong, Cha Ji Hyeon, Kim Seung Tae, Lee Jeeyun

Abstract excerpt

Combination therapy with immune checkpoint inhibitors (ICIs) and chemotherapy has reshaped metastatic gastric cancer (GC) treatment, improving response rate, progression-free survival, and overall survival. We aimed to explore circulating immune cells and elucidate the mechanisms underlying the therapeutic effects of pembrolizumab and capecitabine/oxaliplatin (XELOX) in patients with metastatic GC. Potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41915048
DOI: 10.1007/s00262-025-04263-1
PMCID: PMC13038759

Genes

GC
CCL3
CCL4
CD14
CD27
CD28
CXCL8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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