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The pathogenesis of anti-signal recognition particle necrotizing myopathy: A Review

31 Oct 2022

Abstract excerpt

Immune-mediated necrotizing myopathy (IMNM) is a class of idiopathic inflammatory myopathies. According to the types of antibodies in serum, IMNM can be divided into three subtypes: anti-signal recognition particle (SRP) necrotizing myopathy, 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) necrotizing myopathy, and serum antibody-negative necrotizing myopathy. Different subtypes of IMNM have common...

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PMID: 36411623
DOI: 10.1016/j.biopha.2022.113936

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