Article

Reduced STK11 Expression Is Associated with Vulnerable Phenotypes in Human Carotid Atherosclerotic Plaques

2026-08-13

Abstract excerpt

<title>Abstract</title> <p>Background Vulnerable carotid atherosclerotic plaques are closely associated with ischemic cerebrovascular events, but the molecular mechanisms underlying plaque destabilization remain incompletely understood. STK11 is involved in cellular metabolism, inflammatory regulation, and stress responses; however, its expression pattern in human vulnerable carotid plaques remains unclear. This...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e0460083-946b-5883-909f-dc8154ef26da
DOI: 10.21203/rs.3.rs-10539110/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Reduced STK11 Expression Is Associated with Vulnerable Phenotypes in Human Carotid Atherosclerotic PlaquesDOI 10.21203/rs.3.rs-10539110/v1Read

Proteomics reveals spatial and molecular heterogeneities in advanced atherosclerotic carotid artery plaques.Semantic proximity Read

Autoimmune-like CD8⁺ T Cell Responses Drive Atherosclerotic Plaque Instability and Predict Cardiovascular EventsSemantic proximity Read

Identification and experimental validation of KMO as a critical immune-associated mitochondrial gene in unstable atherosclerotic plaqueSemantic proximity Read

Differential Expression of Peripheral Circulating MicroRNA-146a Between Patients with Atherosclerotic Vulnerable Plaque and Stable Plaque.Semantic proximity Read

Autophagic Marker MAP1LC3B Expression Levels Are Associated with Carotid Atherosclerosis SymptomatologySemantic proximity Read

Profiling of Atherosclerotic Lesions by Gene and Tissue Microarrays Reveals PCSK6 as a Novel Protease in Unstable Carotid AtherosclerosisSemantic proximity Read

Inflammation and Endothelial Function Relevant Genetic Polymorphisms and Carotid Plaque in Chinese Population.Semantic proximity Read

Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability.Semantic proximity Read

Gene expression differences between stroke-associated and asymptomatic carotid plaquesSemantic proximity Read

Single-nucleus RNA sequencing reveals that macrophages and smooth muscle cells promote carotid atherosclerosis progression through mitochondrial autophagySemantic proximity Read

BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque.Semantic proximity Read

Positive association of MMP 14 gene polymorphism with vulnerable carotid plaque formation in a Han Chinese population.Semantic proximity Read