Article
BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque.
International journal of molecular sciences - 9 Dec 2020
Alloza Iraide, Salegi Andrea, Mena Jorge, Navarro Raquel Tulloch, Martin César, Aspichueta Patricia, Salazar Lucía Martínez, Carpio Jon Uriarte, Cagigal Patricia De-la-Hera, Vega Reyes, Triviño Juan Carlos, Freijo Maria Del Mar, Vandenbroeck Koen
Abstract excerpt
Carotid atherosclerotic plaque rupture can lead to cerebrovascular accident (CVA). By comparing RNA-Seq data from vascular smooth muscle cells (VSMC) extracted from carotid atheroma surgically excised from a group of asymptomatic and symptomatic subjects, we identified more than 700 genomic variants associated with symptomatology (p < 0.05). From these, twelve single nucleotide polymorphisms (SNPs) were selected...
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