Article

High rate triggers increased atrial release of BMP10, a biomarker for atrial fibrillation and stroke, which affects ventricular cardiomyocytes

2025-02-27

Abstract excerpt

<h4>Background</h4> Bone morphogenetic protein 10 (BMP10) is a ligand of the TGFβ superfamily secreted mainly by atrial cardiomyocytes. Elevated BMP10 blood concentrations predict atrial fibrillation (AF), AF recurrence after ablation and AF-related cardiovascular complications like stroke. The conditions increasing BMP10 secretion and downstream effects of BMP10 in cardiomyocytes are poorly understood. We assesse...

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Literature Corpus work: e00fd729-b0f4-59a2-b52a-5518dc5d0852
DOI: 10.1101/2025.02.24.25322820

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