Article

The Estrogen Receptor -Isoform (ER ) of the Human Estrogen Receptor Modulates ER Transcriptional Activity and Is a Key Regulator of the Cellular Response to Estrogens and Antiestrogens

1999-12-01

Abstract excerpt

The human estrogen receptor α (ERα) and the recently identified ERβ share a high degree of amino acid homology; however, there are significant differences in regions of these receptors that would be expected to influence transcriptional activity. Consequently, we compared the mechanism(s) by which these receptors regulate target gene transcription, and evaluated the cellular consequences of coexpression of both ER...

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Literature Corpus work: df8af931-6bf8-5dc2-afa2-196c78087fe7
DOI: 10.1210/en.140.12.5566

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