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Article

Estrogen Signaling: A Subtle Balance Between ER and ER

1 Aug 2003

Abstract excerpt

The biological actions of estrogens are mediated by estrogen binding to one of two specific estrogen receptors (ERs) ERalpha and ERbeta, which belong to the nuclear receptor superfamily, a family of ligand-regulated transcription factors. ERalpha and ERbeta are products of different genes and exhibit tissue- and cell-type specific expression. The characterization of mice lacking ERalpha, or ERbeta, or both has...

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PMID: 14993442
DOI: 10.1124/mi.3.5.281

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