Article

The interaction between AF-1 and AF-2 in the two human estrogen receptors

2004-01-01

Abstract excerpt

Estrogen receptors, ERα and ERβ, are members of the large nuclear receptor superfamily of ligand-activated transcription factors. They stimulate the transcription of their target genes by two different activation functions (AF-1 and AF-2). These two activation functions exert their effects independently but can interact with each other in a synergistic manner. The contributions of AF-1 and AF-2 to overall transcri...

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Literature Corpus work: 60e3fa2f-038d-51ae-b95f-82f904cd1a86
DOI: 10.17638/03167691

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