Article
Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease
2019-04-02
Abstract excerpt
<h4>SUMMARY</h4> Cardiovascular diseases (CVD), and in particular cerebrovascular and ischemic heart diseases, are leading causes of death globally. 1 Lowering circulating lipids is an important treatment strategy to reduce risk. 2,3 However, some pharmaceutical mechanisms of reducing CVD may increase risk of fatty liver disease or other metabolic disorders. 4,5,6 To identify potential novel therapeutic target...
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Identifiers and source
- Literature Corpus work
- df7b9e9c-a26f-5144-a1ca-1512307b1e6d
- DOI
- 10.1101/597377
