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Article

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

2019-04-02

Abstract excerpt

<h4>SUMMARY</h4> Cardiovascular diseases (CVD), and in particular cerebrovascular and ischemic heart diseases, are leading causes of death globally. 1 Lowering circulating lipids is an important treatment strategy to reduce risk. 2,3 However, some pharmaceutical mechanisms of reducing CVD may increase risk of fatty liver disease or other metabolic disorders. 4,5,6 To identify potential novel therapeutic target...

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Literature Corpus work
df7b9e9c-a26f-5144-a1ca-1512307b1e6d
DOI
10.1101/597377
Open publication

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Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular diseaseDOI 10.1101/597377
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