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GENETIC DIVERSITY OF <i>T. B. RHODESIENSE</i> SERUM RESISTANCE ASSOCIATED GENE IN MALAWIAN ISOLATES

2024-09-09

Abstract excerpt

<h4>Background</h4> Human African Trypanosomiasis (HAT) is a health burden in most remote areas of Sub-Saharan Africa. Only 2 species of the Trypanosome parasites, namely, T. b. rhodesiense and T. b. gambiense can establish infection in humans whereas other trypanosome parasites are lysed by human serum APOL-1 protein. The mechanism of T. b. gambiense resistance to APOL-1 activity is complex and involves sever...

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Literature Corpus work
df703fa7-d90f-54a7-8c4b-d9b4797ef785
DOI
10.1101/2024.09.07.611819
Open publication

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