Article
Differences in gene expression profiles in early and late stage rhodesiense HAT individuals in Malawi.
PLoS neglected tropical diseases - 1 Dec 2023
Nambala Peter, Mulindwa Julius, Noyes Harry, Alibu Vincent Pius, Nerima Barbara, Namulondo Joyce, Nyangiri Oscar, Matovu Enock, MacLeod Annette, Musaya Janelisa
Abstract excerpt
T. b. rhodesiense is the causative agent of Rhodesian human African trypanosomiasis (r-HAT) in Malawi. Clinical presentation of r-HAT in Malawi varies between foci and differs from East African HAT clinical phenotypes. The purpose of this study was to gain more insights into the transcriptomic profiles of patients with early stage 1 and late stage 2 HAT disease in Malawi. Whole blood from individuals infected...
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