Article
Cell differentiation defines acute and chronic infection cell types in Staphylococcus aureus
11 Sept 2017
Abstract excerpt
A central question to biology is how pathogenic bacteria initiate acute or chronic infections. Here we describe a genetic program for cell-fate decision in the opportunistic human pathogen Staphylococcus aureus, which generates the phenotypic bifurcation of the cells into two genetically identical but different cell types during the course of an infection. Whereas one cell type promotes the formation of biofilms...
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