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Article

Landscape of T cell epitopes displays hot mutations of SARS-CoV-2 variant spikes evading cellular immunity.

Journal of medical virology - 1 Feb 2024

Gan Mengze, Cao Jinge, Zhang Yandi, Fu Hui, Lin Xiaosong, Ouyang Qi, Xu Xinyue, Yuan Yin, Fan Xionglin

Abstract excerpt

The continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been accompanied by the emergence of viral mutations that pose a great challenge to existing vaccine strategies. It is not fully understood with regard to the role of mutations on the SARS-CoV-2 spike protein from emerging viral variants in T cell immunity. In the current study, recombinant eukaryotic plasmids were...

Read the complete abstract on PubMed

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Share to Antibodies, Neutralizing
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

Share to Immunity, Cellular

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Share to Spike Glycoprotein, Coronavirus

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Source

Identifiers

PMID: 38314852
DOI: 10.1002/jmv.29452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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