Article

Systematic characterization of protein structural features of alternative splicing isoforms using AlphaFold 2

2024-02-01

Abstract excerpt

Alternative splicing is an important cellular process in eukaryotes, altering pre-mRNA to yield multiple protein isoforms from a single gene. However, our understanding of the impact of alternative splicing events on protein structures is currently constrained by a lack of sufficient protein structural data. To address this limitation, we employed AlphaFold 2, a cutting-edge protein structure prediction tool, to c...

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Literature Corpus work: df032aa0-bee7-5fa1-8d20-e91be79a4f52
DOI: 10.1101/2024.01.30.578053

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