Article

DeltaMut: An Integrative Database of AlphaFold2-Derived Missense Variant Structures

2026-06-04

Abstract excerpt

The widespread use of next-generation sequencing has led to a surge in the number of identified variants with uncertain effects on protein function. These variants pose a significant challenge in diagnostics and hinder patient treatment strategies. Numerous variant effect predictors (VEPs) are available to assess variant impact, but they primarily rely on sequence-derived information. The recent development of Alp...

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Literature Corpus work: f4cf20cc-9083-51ae-8856-18f96c5bd1a3
DOI: 10.64898/2026.06.03.729798

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