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Article

Verification of alternative splicing variants based on domain integrity, truncation length and intrinsic protein disorder.

Nucleic acids research - 1 Mar 2011

Hegyi Hedi, Kalmar Lajos, Horvath Tamas, Tompa Peter

Abstract excerpt

According to current estimations ∼95% of multi-exonic human protein-coding genes undergo alternative splicing (AS). However, for 4000 human proteins in PDB, only 14 human proteins have structures of at least two alternative isoforms. Surveying these structural isoforms revealed that the maximum i...

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Identifiers

PMID: 20972208
DOI: 10.1093/nar/gkq843
PMCID: PMC3045584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20972208-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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