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Identification of potential changes in protein abundance associated with post-traumatic stress disorder through brain proteome-wide association study

2025-09-02

Abstract excerpt

<h4>Aim</h4> Post-traumatic stress disorder (PTSD) is a common mental disorder with a substantial genetic background. Recent genome-wide association analysis (GWAS) has identified 95 genome-wide significant (GWS) loci in a large cross-ancestry cohort comprising over 1 million samples. However, bridging the GWS findings to potential therapeutic candidates is lagged. <h4>Method</h4> In this study, we integrated th...

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Literature Corpus work
ded8e2f4-aa47-51ba-927f-08e7ce46096c
DOI
10.1101/2025.08.28.25334625
Open publication

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Identification of potential changes in protein abundance associated with post-traumatic stress disorder through brain proteome-wide association studyDOI 10.1101/2025.08.28.25334625
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