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A model for estimating traction force magnitude reveals differential regulation of actomyosin activity and matrix adhesion number in response to smooth muscle cell spreading

2019-04-17

Abstract excerpt

Decreased aortic compliance is associated with ageing and vascular disease, including atherosclerosis and hypertension. Ultimately, changes in aortic compliance are driven by altered ECM composition however, recent findings have identified a cellular component to decreased aortic compliance observed in ageing and hypertension. Vascular smooth muscle cells (VSMCs) line the blood vessel wall and VSMC contraction reg...

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Literature Corpus work
de7feb17-fa2c-529a-bf6e-ef1ee04c0e82
DOI
10.1101/612267
Open publication

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