Article
Biomechanical phenotyping of central arteries in health and disease: advantages of and methods for murine models.
Annals of biomedical engineering - 1 Jul 2013
Ferruzzi J, Bersi M R, Humphrey J D
Abstract excerpt
The stiffness and structural integrity of the arterial wall depends primarily on the organization of the extracellular matrix and the cells that fashion and maintain this matrix. Fundamental to the latter is a delicate balance in the continuous production and removal of structural constituents and the mechanical state in which such turnover occurs. Perturbations in this balance due to genetic mutations, altered...
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