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Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer’s disease mouse model

2020-11-06

Abstract excerpt

Extracellular vesicles (EVs) are secreted by any neuronal cells in the central nervous system (CNS) for molecular clearance, cellular communications and disease spread in multiple neurodegenerative diseases, including Alzheimer’s disease (AD), although their exact molecular mechanism is poorly understood. We hypothesize that high-resolution proteomic profiling of EVs separated from animal models of AD would determ...

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Literature Corpus work
461d3f2f-716a-5039-be29-13071a454053
DOI
10.1101/2020.11.05.369728
Open publication

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Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer’s disease mouse modelDOI 10.1101/2020.11.05.369728
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