Article

Murine cytomegalovirus evolved a cell-cycle regulator (m54.5) within the highly conserved viral DNA polymerase gene

2025-08-04

Abstract excerpt

Ribosome profiling (Ribo-seq) coupled with transcription start site profiling time-course analyses recently unveiled hundreds of novel viral gene products in lytic murine cytomegalovirus (MCMV) infection. One of these is the m54.5 open reading frame (ORF) located within the highly conserved viral DNA polymerase locus (M54). Interestingly, the m54.5 ORF is expressed from its own transcript (m54.5 RNA) with early ge...

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Literature Corpus work: de27ad3c-4bc5-5317-b4c1-ecc9261af795
DOI: 10.1101/2025.08.04.668388

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