Decoding murine cytomegalovirus

Abstract excerpt

The genomes of both human cytomegalovirus (HCMV) and murine cytomegalovirus (MCMV) were first sequenced over 20 years ago. Similar to HCMV, the MCMV genome had initially been proposed to harbor ≈170 open reading frames (ORFs). More recently, omics approaches revealed HCMV gene expression to be substantially more complex comprising several hundreds of translated ORFs. Here, we provide a state-of-the art reannotatio...

Topics

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• Cytomegalovirus and herpesvirus research
• Fibroblasts
• Gene Expression Regulation, Viral
• Genome, Viral
• Herpesvirus Infections and Treatments
• HIV Research and Treatment
• Immune Cell Function and Interaction
• RNA regulation and disease

Identifiers and source

Literature Corpus work

48c182f0-3be9-54e4-af55-077a853aef03

DOI

10.1101/2022.11.10.515907