Article
Characterization of Recombinant β Subunit of Human MUC4 Mucin (rMUC4β)
2021-08-23
Abstract excerpt
MUC4 is a transmembrane mucin expressed on various epithelial surfaces, including respiratory and gastrointestinal tracts, and helps in their lubrication and protection. MUC4 is also aberrantly overexpressed in various epithelial malignancies and functionally contributes to cancer development and progression. MUC4 is putatively cleaved at the GDPH site into a mucin-like α-subunit and a membrane-tethered growth fac...
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Identifiers and source
- Literature Corpus work
- dded3aec-82a9-54bc-bd32-54255420a12b
- DOI
- 10.21203/rs.3.rs-812058/v1