Article

Single-Cell RNA Sequencing Reveals Endothelial Cell Transcriptome Heterogeneity under Homeostatic Laminar Flow

2020-12-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Endothelial cells that form the innermost layer of all vessels exhibit heterogeneous cell behaviors and responses to pro-angiogenic signals that are critical for vascular sprouting and angiogenesis. Once vessels form, remodeling and blood flow lead to endothelial cell quiescence, and homogeneity in cell behaviors and signaling responses. These changes are important for the fu...

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Literature Corpus work: ddb08254-608c-5dcb-840b-21e1e16e85ab
DOI: 10.1101/2020.12.07.414904

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