Article

Single cell ‘omic profiles of human aortic endothelial cells <i>in vitro</i> and human atherosclerotic lesions <i>ex vivo</i> reveals heterogeneity of endothelial subtype and response to activating perturbations

2023-04-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Endothelial cells (ECs), macrophages, and vascular smooth muscle cells (VSMCs) are major cell types in atherosclerosis progression, and heterogeneity in EC sub-phenotypes are becoming increasingly appreciated. Still, studies quantifying EC heterogeneity across whole transcriptomes and epigenomes in both in vitro and in vivo models are lacking. <h4>Approach and Results</h4>...

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Literature Corpus work: 237922b9-52bd-5a5b-a94d-c9c1cda0630e
DOI: 10.1101/2023.04.03.535495

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Single cell ‘omic profiles of human aortic endothelial cells <i>in vitro</i> and human atherosclerotic lesions <i>ex vivo</i> reveals heterogeneity of endothelial subtype and response to activating perturbationsDOI 10.1101/2023.04.03.535495Read

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