Article

Hypoactivity, Abnormal Musculature, and Learning and Memory Defects in slc6a3 zebrafish Mutant Larvae

2021-03-17

Abstract excerpt

<title>Abstract</title> <p>Dopamine (DA) is one of the most common neurotransmitters in living organisms and is involved in the regulation of behavior, physiology, and disease. The dopamine transporter (DAT, encoded by the <italic>slc6a3</italic> gene) re-uptakes dopamine from the synaptic cleft back into neurons, which plays a critical role in regulating dopamine signaling. Clinically, mutations in <italic>slc6a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dda4b3ca-1a74-5b90-8ba1-d0d5cd10e00e
DOI: 10.21203/rs.3.rs-305056/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hypoactivity, Abnormal Musculature, and Learning and Memory Defects in slc6a3 zebrafish Mutant LarvaeDOI 10.21203/rs.3.rs-305056/v1Read

Morphological, behavioral and molecular studies on CRISPR/Cas9-mediated knockout of the NOMO1 gene in zebrafishSemantic proximity Read

Anti-Parkinsonian Drugs Rescue Locomotor Deficits in JIP3 Knockout Zebrafish: Implications for Treating Patients with <i>MAPK8IP3</i> -related Neurodevelopmental DisordersSemantic proximity Read

Zebrafish as a new animal model for movement disorders.Semantic proximity Read

Generation and validation of a D1 dopamine receptor Flpo knock-in mouseSemantic proximity Read

Danio rerio: The Zebrafish in Modern Biomedical ResearchSemantic proximity Read

Zebrafish as a novel model to assess Na+/K(+)-ATPase-related neurological disorders.Semantic proximity Read

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Treated Adult Zebrafish as a Model for Parkinson’s DiseaseSemantic proximity Read

Early motor deficits, sleep dysfunction and reduction in dopaminergic neurons in a park7 -/- zebrafish larval model of Parkinson’s diseaseSemantic proximity Read

Zebrafish Larvae Behavior Models as a Tool for Drug Screenings and Pre-Clinical Trials: A Review.Semantic proximity Read

Orphan cytochrome P450 20A1 CRISPR/Cas 9 mutants and neurobehavioral phenotypes in zebrafishSemantic proximity Read

Forward genetic analysis to identify determinants of dopamine signaling in Caenorhabditis elegans using swimming-induced paralysis.Semantic proximity Read

In the swim of things: recent insights to neurogenetic disorders from zebrafish.Semantic proximity Read