Article

Early motor deficits, sleep dysfunction and reduction in dopaminergic neurons in a park7 -/- zebrafish larval model of Parkinson’s disease

2025-11-14

Abstract excerpt

<title>Abstract</title> <p> Parkinson's Disease (PD) is the fastest-growing neurological disorder and only symptomatic treatment is available. Zebrafish are ideally suited for high-throughput screening of disease modifying drugs and mechanistic studies. Mutations in <italic>park7</italic> are associated with early-onset familial PD. Additionally, altered levels and subcellular location of the <italic>park7</i...

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Literature Corpus work: 852279d3-0071-5c9c-b50c-9bb2c3526601
DOI: 10.21203/rs.3.rs-7848595/v1

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