Article

Association of Gene Variant Type and Location with Breast Cancer Risk in the General Population

2024-10-12

Abstract excerpt

<h4>Importance</h4> Pathogenic variants (PVs) in ATM, BRCA1, BRCA2, CHEK2 , and PALB2 are associated with increased breast cancer risk. However, it is unknown whether breast cancer risk differs by PV type or location in carriers ascertained from the general population. <h4>Objective</h4> To evaluate breast cancer risks associated with PV type and location in ATM, BRCA1, BRCA2, CHEK2 , and PALB2 . <h4>Design</h4> A...

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Literature Corpus work: dd93f4cb-d5b6-5004-979a-6dcaabfed7f6
DOI: 10.1101/2024.10.11.24315237

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