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Totum-448, a polyphenol-rich plant extract, decreases hepatic steatosis and inflammation in diet-induced MASLD mice

2025-04-07

Abstract excerpt

<title>Abstract</title> <p>The increasing prevalence of obesity-driven metabolic dysfunction-associated steatotic liver disease (MASLD) urges the development of new therapeutic strategies. Totum-448 is a unique patented combination of polyphenol-rich plant extracts designed to reduce hepatic steatosis, a risk factor for steatohepatitis and type 2 diabetes. In this study, we investigated the effects of Totum-448 o...

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Literature Corpus work
8d9fd91e-01cc-5130-8c66-eff610c5d8a1
DOI
10.21203/rs.3.rs-6285712/v1
Open publication

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Totum-448, a polyphenol-rich plant extract, decreases hepatic steatosis and inflammation in diet-induced MASLD miceDOI 10.21203/rs.3.rs-6285712/v1
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