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The interferon-ɣ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way

2024-01-24

Abstract excerpt

<h4>ABSTRACT</h4> We determined the transcription profile of AAV2-infected primary human fibroblasts. Subsequent analysis revealed that cells respond to AAV infection through changes in several significantly affected pathways including cell cycle regulation, chromatin modulation, and innate immune responses. Various assays were performed to validate selected differentially expressed genes and confirmed not only t...

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Literature Corpus work
dd752b6d-85a3-55d1-b95c-4e3b65300f39
DOI
10.1101/2024.01.22.576730
Open publication

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The interferon-ɣ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent wayDOI 10.1101/2024.01.22.576730
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