Article

Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer’s Disease Sequencing Project

2018-05-11

Abstract excerpt

The Alzheimer’s Disease Sequencing Project (ADSP) performed whole genome sequencing (WGS) of 584 subjects from 111 multiplex families at three sequencing centers. Genotype calling of single nucleotide variants (SNVs) and insertion-deletion variants (indels) was performed centrally using GATK-HaplotypeCaller and Atlas V2 . The ADSP Quality Control (QC) Working Group applied QC protocols to project-level variant c...

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Literature Corpus work: dd6634c6-fd8d-5d31-9f35-58931bd06fca
DOI: 10.1101/318857

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