Article

Data Descriptor: Human whole exome genotype data for Alzheimer’s Disease

2022-10-13

Abstract excerpt

Bigger sample size can help to identify new genetic variants contributing to an increased risk of developing Alzheimer’s disease. However, the heterogeneity of the whole-exome sequencing (WES) data generation methods presents a challenge to a joint analysis. Here we present a bioinformatics strategy for joint calling 20,504 WES samples collected across nine studies and sequenced using ten different capture kits in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d01e4021-37b8-564a-b176-a828a2abfd2e
DOI: 10.1101/2022.10.11.511653

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Data Descriptor: Human whole exome genotype data for Alzheimer’s DiseaseDOI 10.1101/2022.10.11.511653Read

Human whole-exome genotype data for Alzheimer's disease.Semantic proximity Read

A Specialized Reference Panel with Structural Variants Integration for Improving Genotype Imputation in Alzheimer’s Disease and Related Dementias (ADRD)Semantic proximity Read

VCPA: genomic variant calling pipeline and data management tool for Alzheimer’s Disease Sequencing ProjectSemantic proximity Read

Alzheimer’s Disease Sequencing Project Release 4 Whole Genome Sequencing DatasetSemantic proximity Read

Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset.Semantic proximity Read

NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases.Semantic proximity Read

Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer’s Disease Sequencing ProjectSemantic proximity Read

A fast and robust strategy to remove variant level artifacts in Alzheimer’s Disease Sequencing Project dataSemantic proximity Read

Alzheimer’s Disease variant portal (ADVP): a catalog of genetic findings for Alzheimer’s DiseaseSemantic proximity Read

Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.Semantic proximity Read

Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.Semantic proximity Read

NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases.Semantic proximity Read