Back to search

Article

Self-Replicating RNA Viruses for Vaccine Development Against Infectious Diseases and Cancer

2021-07-12

Abstract excerpt

Alphaviruses, flaviviruses, measles viruses and rhabdoviruses are enveloped single-stranded RNA viruses, which have been engineered as expression vector systems for recombinant protein expression and vaccine development. Due to the presence of non-structural genes encoding the replicase complex, a 200,000-fold amplification of viral RNA occurs in the cytoplasm of infected cells providing extreme transgene expressi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
dd545218-3b06-5fe6-92d2-fbd5b0d20515
DOI
10.20944/preprints202107.0261.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Self-Replicating RNA Viruses for Vaccine Development Against Infectious Diseases and CancerDOI 10.20944/preprints202107.0261.v1
Self-Amplifying RNA Viruses as RNA VaccinesSemantic proximity
Self-Replicating RNA Viruses for RNA TherapeuticsSemantic proximity
Self-Replicating Alphaviruses: From Pathogens to Therapeutic AgentsSemantic proximity
Self-Replicating Alphaviruses: From Pathogens to Therapeutic AgentsSemantic proximity
Self-replicating alphavirus RNA vaccinesSemantic proximity
Therapeutic Applications for Oncolytic Self-Replicating RNA VirusesSemantic proximity
Next generation self-replicating RNA vectors for vaccines and immunotherapiesSemantic proximity
Replicon RNA Viral Vectors as VaccinesSemantic proximity
Trans-Amplifying RNA: A Journey from Alphavirus Research to Future VaccinesSemantic proximity
Replicon RNA vaccines: design, delivery, and immunogenicity in infectious diseases and cancerSemantic proximity
Replicating and non-replicating viral vectors for vaccine developmentSemantic proximity
Self-Amplifying RNA: A Second Revolution of mRNA Vaccines against COVID-19Semantic proximity
Select a neighboring publication to make it the new centre.