Self-Amplifying RNA Viruses as RNA Vaccines

Abstract excerpt

Single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses and rhabdoviruses are characterized by their capacity of highly efficient self-amplification of RNA in host cells, which make them attractive vehicles for vaccine development. Particularly, alphaviruses and flaviviruses can be administered as recombinant particles, layered DNA/RNA plasmid vectors carrying the RNA replicon and even RNA...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Viral Infections and Outbreaks Research
• Share to Viral Infections and Vectors
• Share to Virology and Viral Diseases