Article
Serpine1 plays a critical role in Th17 cell differentiation and psoriasis pathogenesis
2025-05-12
Abstract excerpt
A large body of evidence indicates that Th17 cells play essential roles in mucosal immune responses and trigger autoimmune diseases, including multiple sclerosis, inflammatory bowel disease, and psoriasis. Targeting Th17 cells holds promise for therapeutic innovation. However, the molecular mechanisms underlying Th17 cell differentiation remain poorly understood. Here, we found that Serpine1 was preferentially ind...
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Identifiers and source
- Literature Corpus work
- dd3ad4cc-734b-5cf3-ade7-fac27effd51e
- DOI
- 10.1101/2025.05.08.652800