Article

SIX1 Down-Regulation Influence Drug Resistance, Epithelial-Mesenchymal Transcription Factors and Self-Renewal Capacity in Hepatocellular Carcinoma

2021-04-29

Abstract excerpt

<title>Abstract</title> <p>Sine oculis homeoprotein 1 (SIX1) was discovered to exert an essential role in embryonic development and it was also identified to be re-activated in various types of mammalian cancer. Immunohistochemical and SIX1 gene expression analyses were performed to determine the prognostic role of SIX1 expression. SIX1 expression was suppressed by short hairpin RNA transduction in the SNU398 HCC...

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Literature Corpus work: dd248c5d-6121-54cf-9bb0-13becd32a8d6
DOI: 10.21203/rs.3.rs-376584/v1

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