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Article

SIX1 amplification modulates stemness and tumorigenesis in breast cancer

29 Nov 2023

Abstract excerpt

BACKGROUND: Sine oculis homeobox homolog 1 (SIX1) is a transcription factor that has recently been identified as a crucial regulator of embryonic development and tumorigenesis. SIX1 is upregulated in different types of tumors, including breast cancer. However, the role and mechanism of SIX1 upregulation in breast cancer carcinogenesis remains uncertain. METHODS: In this study, we utilized various databases such...

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PMID: 38031089
DOI: 10.1186/s12967-023-04679-2

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