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Exploring the Causal Relationship Between Body Mass Index and Kidney Function Using Tissue-Partitioned Mendelian Randomization

2025-08-21

Abstract excerpt

<h4>Background</h4> Chronic kidney disease (CKD) represents a leading non-communicable disease, significantly contributing to global morbidity and mortality. Mendelian randomization studies (MR) have been integral in providing robust evidence that increased body mass index (BMI) has a causal impact on CKD. However, dissecting which specific mechanisms are primarily responsible for disease development remains chal...

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Literature Corpus work
dd1e0076-807c-5dee-9a42-b4d3617b07ec
DOI
10.1101/2025.08.19.25333885
Open publication

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Exploring the Causal Relationship Between Body Mass Index and Kidney Function Using Tissue-Partitioned Mendelian RandomizationDOI 10.1101/2025.08.19.25333885
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