Back to search

Article

Causal Effects of Life Course Adiposity on Chronic Kidney Disease: A Mendelian Randomization Study

2021-08-10

Abstract excerpt

<h4>Background: </h4> Obesity is reported to be tightly correlated the development of chronic kidney disease (CKD). However, whether there exists causation is unknown, and it remains controversial about the role of obesity in CKD is protective or destructive. In this study, we try to infer the causal relationship between life course adiposity and CKD, to provide a rationale for obesity management in CKD patients....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b12a5bd0-b386-56cc-8113-1ae33ae04e72
DOI
10.21203/rs.3.rs-746367/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Causal Effects of Life Course Adiposity on Chronic Kidney Disease: A Mendelian Randomization StudyDOI 10.21203/rs.3.rs-746367/v1
Phenome-wide investigation of the causal associations between childhood BMI and adult outcomes: A two-sample Mendelian randomization studySemantic proximity
Obesity as a cause of kidney disease – insights from Mendelian randomisation studiesSemantic proximity
Causality of visceral adipose tissue on chronic kidney disease and renal function measure indicators, and mediation role of hypertension: Mendelian randomization studySemantic proximity
Contributions of obesity to kidney health and disease: insights from Mendelian randomization and the human kidney transcriptomicsSemantic proximity
Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization studySemantic proximity
Systematic assessment of obesity-related risk factors in renal cancer etiology: A longitudinal risk and Mendelian randomization analysis.Semantic proximity
Life-course adiposity and severe liver disease: a Mendelian randomization analysis.Semantic proximity
Obesity and Kidney Function: A Two-Sample Mendelian Randomization StudySemantic proximity
Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney diseaseSemantic proximity
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney diseaseSemantic proximity
Life-course obesity and heart failure: a two-sample Mendelian randomization study.Semantic proximity
Causal Effects of Genetically Predicted Cardiovascular Risk Factors on Chronic Kidney Disease: A Two-Sample Mendelian Randomization StudySemantic proximity
Select a neighboring publication to make it the new centre.