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Obesity and Kidney Function: A Two-Sample Mendelian Randomization Study

3 Nov 2021

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BACKGROUND: Obesity and type 2 diabetes (T2D) are correlated risk factors for chronic kidney disease (CKD). METHODS: Using summary data from GIANT (Genetic Investigation of Anthropometric Traits), DIAGRAM (DIAbetes Genetics Replication And Meta-analysis), and CKDGen (CKD Genetics), we examined causality and directionality of the association between obesity and kidney function. Bidirectional 2-sample Mendelian...

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PMID: 34922334
DOI: 10.1093/clinchem/hvab249

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