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Article

Diosmetin alleviates liver inflammation by improving liver sinusoidal endothelial cell dysfunction

2023-10-25

Abstract excerpt

<h4>Background & Aims</h4> Tumor necrosis factor-alpha (TNFα) induces pro-inflammatory activation in liver sinusoidal endothelial cells (LSEC) and liver inflammation. However, knowledge about whether modulating LSEC activation can alleviate liver inflammation is scarce. This study aimed to establish and validate an animal model mimicking LSEC dysfunction observed in patients with elevated plasma levels of TNFα, a...

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Literature Corpus work
dd0e77a0-939b-554a-ba6d-4a7033358c9a
DOI
10.1101/2023.10.23.563468
Open publication

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Diosmetin alleviates liver inflammation by improving liver sinusoidal endothelial cell dysfunctionDOI 10.1101/2023.10.23.563468
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